1lv8: Difference between revisions
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==Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit== | ==Crystal structure of calf spleen purine nucleoside phosphorylase in a new space group with full trimer in the asymmetric unit== | ||
<StructureSection load='1lv8' size='340' side='right' caption='[[1lv8]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='1lv8' size='340' side='right'caption='[[1lv8]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1lv8]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1lv8]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV8 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9PP:2,6-DIAMINO-(S)-9-[2-(PHOSPHONOMETHOXY)PROPYL]PURINE'>9PP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv8 OCA], [https://pdbe.org/1lv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv8 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv8 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PNPH_BOVIN PNPH_BOVIN] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv8_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv8_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 1lv8" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1lv8" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Purine nucleoside phosphorylase 3D structures|Purine nucleoside phosphorylase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Bos taurus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Bzowska | [[Category: Bzowska A]] | ||
[[Category: Frank | [[Category: Frank J]] | ||
[[Category: Holy | [[Category: Holy A]] | ||
[[Category: Koellner | [[Category: Koellner G]] | ||
[[Category: Raszewski | [[Category: Raszewski G]] | ||
[[Category: Steiner | [[Category: Steiner T]] | ||
[[Category: Stroh | [[Category: Stroh A]] | ||
[[Category: Wielgus-Kutrowska | [[Category: Wielgus-Kutrowska B]] | ||