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[[Image:1iz9.jpg|left|200px]]


{{Structure
==Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8==
|PDB= 1iz9 |SIZE=350|CAPTION= <scene name='initialview01'>1iz9</scene>, resolution 2.00&Aring;
<StructureSection load='1iz9' size='340' side='right'caption='[[1iz9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1iz9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IZ9 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iz9 OCA], [https://pdbe.org/1iz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iz9 RCSB], [https://www.ebi.ac.uk/pdbsum/1iz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iz9 ProSAT], [https://www.topsan.org/Proteins/RSGI/1iz9 TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iz9 OCA], [http://www.ebi.ac.uk/pdbsum/1iz9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1iz9 RCSB]</span>
[https://www.uniprot.org/uniprot/MDH_THETH MDH_THETH] Catalyzes the reversible oxidation of malate to oxaloacetate.
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/1iz9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iz9 ConSurf].
<div style="clear:both"></div>


'''Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8'''
==See Also==
 
*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1IZ9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IZ9 OCA].
[[Category: Large Structures]]
[[Category: Malate dehydrogenase]]
[[Category: Single protein]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Hamada, K.]]
[[Category: Hamada K]]
[[Category: Hasegawa, T.]]
[[Category: Hasegawa T]]
[[Category: Hirose, R.]]
[[Category: Hirose R]]
[[Category: Kuramitsu, S.]]
[[Category: Kuramitsu S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yamano A]]
[[Category: Yamano, A.]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rossman fold]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:26:49 2008''

Latest revision as of 10:13, 25 October 2023

Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8

Structural highlights

1iz9 is a 2 chain structure with sequence from Thermus thermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

MDH_THETH Catalyzes the reversible oxidation of malate to oxaloacetate.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1iz9, resolution 2.00Å

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OCA
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