1iz9: Difference between revisions

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[[Image:1iz9.jpg|left|200px]]<br /><applet load="1iz9" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1iz9, resolution 2.00&Aring;" />
'''Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8'''<br />


==About this Structure==
==Crystal Structure of Malate Dehydrogenase from Thermus thermophilus HB8==
1IZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Active as [http://en.wikipedia.org/wiki/Malate_dehydrogenase Malate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.37 1.1.1.37] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IZ9 OCA].  
<StructureSection load='1iz9' size='340' side='right'caption='[[1iz9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Malate dehydrogenase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1iz9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IZ9 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iz9 OCA], [https://pdbe.org/1iz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iz9 RCSB], [https://www.ebi.ac.uk/pdbsum/1iz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iz9 ProSAT], [https://www.topsan.org/Proteins/RSGI/1iz9 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MDH_THETH MDH_THETH] Catalyzes the reversible oxidation of malate to oxaloacetate.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/1iz9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iz9 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Hamada, K.]]
[[Category: Hamada K]]
[[Category: Hasegawa, T.]]
[[Category: Hasegawa T]]
[[Category: Hirose, R.]]
[[Category: Hirose R]]
[[Category: Kuramitsu, S.]]
[[Category: Kuramitsu S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yamano A]]
[[Category: Yamano, A.]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rossman fold]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
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