5lx3: Difference between revisions

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'''Unreleased structure'''


The entry 5lx3 is ON HOLD  until Paper Publication
==CRYSTAL STRUCTURE OF VISFATIN IN COMPLEX WITH SAR154782.==
<StructureSection load='5lx3' size='340' side='right'caption='[[5lx3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5lx3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LX3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7A1:6-[4-[(6-azanylpyridin-3-yl)methylcarbamoylamino]-3-fluoranyl-phenyl]-2-(ethylamino)-~{N}-(2-piperidin-1-ylethyl)pyridine-3-carboxamide'>7A1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lx3 OCA], [https://pdbe.org/5lx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lx3 RCSB], [https://www.ebi.ac.uk/pdbsum/5lx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lx3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NAMPT_HUMAN NAMPT_HUMAN] Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity).


Authors: Bertrand, T., Marquette, J.P.
==See Also==
 
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
Description: CRYSTAL STRUCTURE OF VISFATIN IN COMPLEX WITH SAR154782.
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Marquette, J.P]]
[[Category: Homo sapiens]]
[[Category: Bertrand, T]]
[[Category: Large Structures]]
[[Category: Bertrand T]]
[[Category: Marquette JP]]

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