5lnt: Difference between revisions

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<StructureSection load='5lnt' size='340' side='right'caption='[[5lnt]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
<StructureSection load='5lnt' size='340' side='right'caption='[[5lnt]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5lnt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LNT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LNT FirstGlance]. <br>
<table><tr><td colspan='2'>[[5lnt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LNT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KPR:[(~{E},4~{S})-4-AZANYL-3-OXIDANYLIDENE-PENT-1-ENYL]+DIHYDROGEN+PHOSPHATE'>KPR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.32&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDX11, PDX1L1, At2g38230, F16M14.16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KPR:[(~{E},4~{S})-4-AZANYL-3-OXIDANYLIDENE-PENT-1-ENYL]+DIHYDROGEN+PHOSPHATE'>KPR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyridoxal_5'-phosphate_synthase_(glutamine_hydrolyzing) Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.6 4.3.3.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lnt OCA], [https://pdbe.org/5lnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lnt RCSB], [https://www.ebi.ac.uk/pdbsum/5lnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lnt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5lnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lnt OCA], [http://pdbe.org/5lnt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lnt RCSB], [http://www.ebi.ac.uk/pdbsum/5lnt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lnt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PDX11_ARATH PDX11_ARATH]] Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.<ref>PMID:16157873</ref> <ref>PMID:17468224</ref>
[https://www.uniprot.org/uniprot/PDX11_ARATH PDX11_ARATH] Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.<ref>PMID:16157873</ref> <ref>PMID:17468224</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Begley, T P]]
[[Category: Begley TP]]
[[Category: Ealick, S E]]
[[Category: Ealick SE]]
[[Category: Evans, G]]
[[Category: Evans G]]
[[Category: Guedez, G]]
[[Category: Guedez G]]
[[Category: Hanes, J W]]
[[Category: Hanes JW]]
[[Category: Rodrigues, M J]]
[[Category: Rodrigues MJ]]
[[Category: Royant, A]]
[[Category: Royant A]]
[[Category: Sinning, I]]
[[Category: Sinning I]]
[[Category: Strohmeier, M]]
[[Category: Strohmeier M]]
[[Category: Tews, I]]
[[Category: Tews I]]
[[Category: Weber, S]]
[[Category: Weber S]]
[[Category: Windeisen, V]]
[[Category: Windeisen V]]
[[Category: Zhang, Y]]
[[Category: Zhang Y]]
[[Category: Beta/alpha barrel]]
[[Category: Glutamine amidotransferase]]
[[Category: Lyase]]
[[Category: Pyridoxal phosphate synthase]]
[[Category: Vitamin b6 biosythesis]]

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