7ts5: Difference between revisions

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-'''Unreleased structure'''
-The entry 7ts5 is ON HOLD  until Paper Publication
+==Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine==
+<StructureSection load='7ts5' size='340' side='right'caption='[[7ts5]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7ts5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TS5 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K9C:4-methyl-6-[3-(methylamino)prop-1-yn-1-yl]pyridin-2-amine'>K9C</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ts5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ts5 OCA], [https://pdbe.org/7ts5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ts5 RCSB], [https://www.ebi.ac.uk/pdbsum/7ts5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ts5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NOS1_HUMAN NOS1_HUMAN] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
-Authors: Li, H., Poulos, T.L.
+==See Also==
+*[[Nitric Oxide Synthase 3D structures|Nitric Oxide Synthase 3D structures]]
-Description: Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Li, H]]
+[[Category: Homo sapiens]]
-[[Category: Poulos, T.L]]
+[[Category: Large Structures]]
+[[Category: Li H]]
+[[Category: Poulos TL]]