7t1c: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7t1c is ON HOLD  until Paper Publication
+==Crystal structure of RUBISCO from Sulfurivirga caldicuralii==
+<StructureSection load='7t1c' size='340' side='right'caption='[[7t1c]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7t1c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurivirga_caldicuralii Sulfurivirga caldicuralii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7T1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7T1C FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7t1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7t1c OCA], [https://pdbe.org/7t1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7t1c RCSB], [https://www.ebi.ac.uk/pdbsum/7t1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7t1c ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A0A1N6DK16_9GAMM A0A1N6DK16_9GAMM]
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Oligomerization is a core structural feature that defines the form and function of many proteins. Most proteins form molecular complexes; however, there remains a dearth of diversity-driven structural studies investigating the evolutionary trajectory of these assemblies. Ribulose-1,5-bisphosphate carboxylase-oxygenase (RuBisCO) is one such enzyme that adopts multiple assemblies, although the origins and distribution of its different oligomeric states remain cryptic. Here, we retrace the evolution of ancestral and extant form II RuBisCOs, revealing a complex and diverse history of oligomerization. We structurally characterize a newly discovered tetrameric RuBisCO, elucidating how solvent-exposed surfaces can readily adopt new interactions to interconvert or give rise to new oligomeric states. We further use these principles to engineer and demonstrate how changes in oligomerization can be mediated by relatively few mutations. Our findings yield insight into how structural plasticity may give rise to new oligomeric states.
-Authors: Pereira, J.H., Liu, A.K., Shih, P.M., Adams, P.D.
+Structural plasticity enables evolution and innovation of RuBisCO assemblies.,Liu AK, Pereira JH, Kehl AJ, Rosenberg DJ, Orr DJ, Chu SKS, Banda DM, Hammel M, Adams PD, Siegel JB, Shih PM Sci Adv. 2022 Aug 26;8(34):eadc9440. doi: 10.1126/sciadv.adc9440. Epub 2022 Aug, 26. PMID:36026446<ref>PMID:36026446</ref>
-Description: Crystal structure of RUBISCO from Sulfurivirga caldicuralii
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>
-[[Category: Adams, P.D]]
+<div class="pdbe-citations 7t1c" style="background-color:#fffaf0;"></div>
-[[Category: Pereira, J.H]]
+== References ==
-[[Category: Liu, A.K]]
+<references/>
-[[Category: Shih, P.M]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Sulfurivirga caldicuralii]]
+[[Category: Adams PD]]
+[[Category: Liu AK]]
+[[Category: Pereira JH]]
+[[Category: Shih PM]]