5lew: Difference between revisions

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<StructureSection load='5lew' size='340' side='right'caption='[[5lew]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5lew' size='340' side='right'caption='[[5lew]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5lew]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LEW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LEW FirstGlance]. <br>
<table><tr><td colspan='2'>[[5lew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LEW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5lew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lew OCA], [http://pdbe.org/5lew PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lew RCSB], [http://www.ebi.ac.uk/pdbsum/5lew PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lew ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lew OCA], [https://pdbe.org/5lew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lew RCSB], [https://www.ebi.ac.uk/pdbsum/5lew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lew ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPO3A_MYCTU DPO3A_MYCTU]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity).  
[https://www.uniprot.org/uniprot/DPO3A_MYCTU DPO3A_MYCTU] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Banos-Mateos, S]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Lamers, M H]]
[[Category: Banos-Mateos S]]
[[Category: Lang, U F]]
[[Category: Lamers MH]]
[[Category: Maslen, S L]]
[[Category: Lang UF]]
[[Category: Skehel, J M]]
[[Category: Maslen SL]]
[[Category: Dna polymerase multi-domain]]
[[Category: Skehel JM]]
[[Category: Transferase]]

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