5lbt: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 5lbt is ON HOLD
+==Structure of the human quinone reductase 2 (NQO2) in complex with imiquimod==
+<StructureSection load='5lbt' size='340' side='right'caption='[[5lbt]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5lbt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LBT FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6T0:1-(2-METHYLPROPYL)IMIDAZO[4,5-C]QUINOLIN-4-AMINE'>6T0</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbt OCA], [https://pdbe.org/5lbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lbt RCSB], [https://www.ebi.ac.uk/pdbsum/5lbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbt ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
-Authors: Schneider, S., Gross, O.
+==See Also==
+*[[Quinone reductase 3D structures|Quinone reductase 3D structures]]
-Description: Structure of the human quinone reductase 2 (NQO2) in complex with imiquimod
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Gross, O]]
+__TOC__
-[[Category: Schneider, S]]
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Gross O]]
+[[Category: Schneider S]]