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==Crystal structure of TTHB099, a transcriptional regulator CRP family from Thermus thermophilus HB8== | ==Crystal structure of TTHB099, a transcriptional regulator CRP family from Thermus thermophilus HB8== | ||
<StructureSection load='3b02' size='340' side='right' caption='[[3b02]], [[Resolution|resolution]] 1.92Å' scene=''> | <StructureSection load='3b02' size='340' side='right'caption='[[3b02]], [[Resolution|resolution]] 1.92Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3b02]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3b02]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zdb 2zdb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B02 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B02 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b02 OCA], [https://pdbe.org/3b02 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b02 RCSB], [https://www.ebi.ac.uk/pdbsum/3b02 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b02 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/LDRP_THET8 LDRP_THET8] Activates transcription. Positively regulates PcrtB promoter upstream of the crtB operon in a cAMP-independent manner. Regulated genes include genes encoding DNA photolyase, phytoene synthase and cytochrome P450 monooxygenase, which are involved in carotenoid biosynthesis. Positively regulates the light-inducible gene cluster in the megaplasmid in a cAMP-independent manner.[UniProtKB:Q746J8] | |||
==See Also== | ==See Also== | ||
*[[Nucleoprotein|Nucleoprotein]] | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Thermus thermophilus HB8]] | ||
[[Category: | [[Category: Agari Y]] | ||
[[Category: | [[Category: Kuramitsu S]] | ||
[[Category: Shinkai | [[Category: Shinkai A]] | ||
Latest revision as of 11:50, 11 October 2023
Crystal structure of TTHB099, a transcriptional regulator CRP family from Thermus thermophilus HB8Crystal structure of TTHB099, a transcriptional regulator CRP family from Thermus thermophilus HB8
Structural highlights
FunctionLDRP_THET8 Activates transcription. Positively regulates PcrtB promoter upstream of the crtB operon in a cAMP-independent manner. Regulated genes include genes encoding DNA photolyase, phytoene synthase and cytochrome P450 monooxygenase, which are involved in carotenoid biosynthesis. Positively regulates the light-inducible gene cluster in the megaplasmid in a cAMP-independent manner.[UniProtKB:Q746J8] See Also |
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