7y1k: Difference between revisions
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==Structure of SUR2A in complex with Mg-ATP, Mg-ADP and repaglinide in the inward-facing conformation== | |||
<StructureSection load='7y1k' size='340' side='right'caption='[[7y1k]], [[Resolution|resolution]] 3.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7y1k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y1K FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BJX:Repaglinide'>BJX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y1k OCA], [https://pdbe.org/7y1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y1k RCSB], [https://www.ebi.ac.uk/pdbsum/7y1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y1k ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ABCC9_RAT ABCC9_RAT] Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Chen L]] | |||
[[Category: Ding D]] | |||
[[Category: Hou T]] | |||
Latest revision as of 11:25, 11 October 2023
Structure of SUR2A in complex with Mg-ATP, Mg-ADP and repaglinide in the inward-facing conformationStructure of SUR2A in complex with Mg-ATP, Mg-ADP and repaglinide in the inward-facing conformation
Structural highlights
FunctionABCC9_RAT Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. |
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