6vyo: Difference between revisions
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==Crystal structure of RNA binding domain of nucleocapsid phosphoprotein from SARS coronavirus 2== | ==Crystal structure of RNA binding domain of nucleocapsid phosphoprotein from SARS coronavirus 2== | ||
< | <SX load='6vyo' size='340' side='right' viewer='molstar' caption='[[6vyo]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6vyo]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6vyo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VYO FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vyo OCA], [https://pdbe.org/6vyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vyo RCSB], [https://www.ebi.ac.uk/pdbsum/6vyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vyo ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/NCAP_SARS2 NCAP_SARS2] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. | |||
==See Also== | |||
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | |||
__TOC__ | __TOC__ | ||
</ | </SX> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Severe acute respiratory syndrome coronavirus 2]] | ||
[[Category: Chang C]] | |||
[[Category: Chang | [[Category: Endres M]] | ||
[[Category: Endres | [[Category: Godzik A]] | ||
[[Category: Godzik | [[Category: Jedrzejczak R]] | ||
[[Category: Jedrzejczak | [[Category: Joachimiak A]] | ||
[[Category: Joachimiak | [[Category: Kim Y]] | ||
[[Category: Kim | [[Category: Maltseva N]] | ||
[[Category: Maltseva | [[Category: Michalska K]] | ||
[[Category: Michalska | |||
Latest revision as of 11:22, 11 October 2023
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