6ub9: Difference between revisions

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 <StructureSection load='6ub9' size='340' side='right'caption='[[6ub9]], [[Resolution|resolution]] 2.78&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6ub9]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6dua 6dua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UB9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UB9 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6ub9]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6dua 6dua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UB9 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=H9V:(2R,3S,4R)-3-(4-chloro-2,6-difluoro[1,1-biphenyl]-4-yl)-4-(fluoromethyl)azetidine-2-carbonitrile'>H9V</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=P1T:2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC+ACID'>P1T</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.783&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpA, Rv1613, MTCY01B2.05 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU]), trpB, Rv1612, MTCY01B2.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=H9V:(2R,3S,4R)-3-(4-chloro-2,6-difluoro[1,1-biphenyl]-4-yl)-4-(fluoromethyl)azetidine-2-carbonitrile'>H9V</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=P1T:2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC+ACID'>P1T</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ub9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ub9 OCA], [https://pdbe.org/6ub9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ub9 RCSB], [https://www.ebi.ac.uk/pdbsum/6ub9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ub9 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ub9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ub9 OCA], [http://pdbe.org/6ub9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ub9 RCSB], [http://www.ebi.ac.uk/pdbsum/6ub9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ub9 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [[http://www.uniprot.org/uniprot/TRPB_MYCTU TRPB_MYCTU]] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine (By similarity).
+[https://www.uniprot.org/uniprot/TRPA_MYCTU TRPA_MYCTU] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
+==See Also==
+*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
 __TOC__
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Myctu]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
-[[Category: Tryptophan synthase]]
+[[Category: Chang C]]
-[[Category: Structural genomic]]
+[[Category: Jedrzejczak R]]
-[[Category: Chang, C]]
+[[Category: Joachimiak A]]
-[[Category: Jedrzejczak, R]]
+[[Category: Maltseva NI]]
-[[Category: Joachimiak, A]]
+[[Category: McCarren P]]
-[[Category: Maltseva, N I]]
+[[Category: Michalska K]]
-[[Category: McCarren, P]]
+[[Category: Nag PP]]
-[[Category: Michalska, K]]
+[[Category: Satchell K]]
-[[Category: Nag, P P]]
-[[Category: Satchell, K]]
-[[Category: Allostery]]
-[[Category: Amino acid biosynthesis]]
-[[Category: Csgid]]
-[[Category: Heterotetramer]]
-[[Category: Lyase-lyase inhibitor complex]]
-[[Category: Plp]]
-[[Category: Substrate channeling]]