6pgs: Difference between revisions

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New page: '''Unreleased structure''' The entry 6pgs is ON HOLD Authors: Eger, B.T., Morizumi, T., Ernst, O.P. Description: Crystal structure of bovine opsin with citronellol bound [[Category: Un...
 
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'''Unreleased structure'''


The entry 6pgs is ON HOLD
==Crystal structure of bovine opsin with geraniol bound==
<StructureSection load='6pgs' size='340' side='right'caption='[[6pgs]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6pgs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PGS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.905&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=64Z:GERANIOL'>64Z</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pgs OCA], [https://pdbe.org/6pgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pgs RCSB], [https://www.ebi.ac.uk/pdbsum/6pgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pgs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>


Authors: Eger, B.T., Morizumi, T., Ernst, O.P.
==See Also==
 
*[[Rhodopsin 3D structures|Rhodopsin 3D structures]]
Description: Crystal structure of bovine opsin with citronellol bound
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Ernst, O.P]]
__TOC__
[[Category: Morizumi, T]]
</StructureSection>
[[Category: Eger, B.T]]
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Eger BT]]
[[Category: Ernst OP]]
[[Category: Morizumi T]]

Latest revision as of 10:29, 11 October 2023

Crystal structure of bovine opsin with geraniol boundCrystal structure of bovine opsin with geraniol bound

Structural highlights

6pgs is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.905Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

OPSD_BOVIN Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).[1] [2]

See Also

References

  1. ↑ Nakamichi H, Okada T. Local peptide movement in the photoreaction intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12729-34. Epub 2006 Aug 14. PMID:16908857
  2. ↑ Salom D, Lodowski DT, Stenkamp RE, Le Trong I, Golczak M, Jastrzebska B, Harris T, Ballesteros JA, Palczewski K. Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16123-8. Epub 2006 Oct 23. PMID:17060607

6pgs, resolution 2.91Å

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