6ojh: Difference between revisions
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==Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine== | |||
<StructureSection load='6ojh' size='340' side='right'caption='[[6ojh]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ojh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OJH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MV4:7-[(3R)-3-aminopyrrolidin-1-yl]-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine'>MV4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ojh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ojh OCA], [https://pdbe.org/6ojh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ojh RCSB], [https://www.ebi.ac.uk/pdbsum/6ojh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ojh ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ACCC_HAEIN ACCC_HAEIN] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | |||
==See Also== | |||
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Haemophilus influenzae Rd KW20]] | ||
[[Category: Cirz | [[Category: Large Structures]] | ||
[[Category: | [[Category: Andrews LD]] | ||
[[Category: | [[Category: Cirz R]] | ||
[[Category: | [[Category: Cohen F]] | ||
[[Category: | [[Category: Dozzo P]] | ||
[[Category: | [[Category: Haglund CM]] | ||
[[Category: | [[Category: Hilderbrandt DJ]] | ||
[[Category: | [[Category: Kane TR]] | ||
[[Category: | [[Category: Linsell MS]] | ||
[[Category: | [[Category: Machajewski T]] | ||
[[Category: | [[Category: McEnroe G]] | ||
[[Category: | [[Category: Neau DB]] | ||
[[Category: | [[Category: Pakhomova S]] | ||
[[Category: | [[Category: Pogliano J]] | ||
[[Category: | [[Category: Serio AW]] | ||
[[Category: Wlasichuk | [[Category: Sharp M]] | ||
[[Category: Waldrop GL]] | |||
[[Category: Wlasichuk KB]] | |||
Latest revision as of 10:11, 11 October 2023
Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amineCrystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine
Structural highlights
FunctionACCC_HAEIN This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. See Also |
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