6me5: Difference between revisions
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<StructureSection load='6me5' size='340' side='right'caption='[[6me5]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='6me5' size='340' side='right'caption='[[6me5]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6me5]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6me5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ME5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ME5 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AWY:~{N}-[2-(7-methoxynaphthalen-1-yl)ethyl]ethanamide'>AWY</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AWY:~{N}-[2-(7-methoxynaphthalen-1-yl)ethyl]ethanamide'>AWY</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6me5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6me5 OCA], [https://pdbe.org/6me5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6me5 RCSB], [https://www.ebi.ac.uk/pdbsum/6me5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6me5 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [https://www.uniprot.org/uniprot/Q9V2J8_PYRAB Q9V2J8_PYRAB] [https://www.uniprot.org/uniprot/MTR1A_HUMAN MTR1A_HUMAN] High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Batyuk | [[Category: Pyrococcus abyssi GE5]] | ||
[[Category: Brehm | [[Category: Batyuk A]] | ||
[[Category: Cherezov | [[Category: Brehm W]] | ||
[[Category: Gati | [[Category: Cherezov V]] | ||
[[Category: Grandner | [[Category: Gati C]] | ||
[[Category: Grant | [[Category: Grandner JM]] | ||
[[Category: Han | [[Category: Grant TD]] | ||
[[Category: Ishchenko | [[Category: Han GW]] | ||
[[Category: Johansson | [[Category: Ishchenko A]] | ||
[[Category: Katritch | [[Category: Johansson LC]] | ||
[[Category: Liu | [[Category: Katritch V]] | ||
[[Category: Madsen | [[Category: Liu W]] | ||
[[Category: McCorvy | [[Category: Madsen C]] | ||
[[Category: Michaelian | [[Category: McCorvy JD]] | ||
[[Category: Olsen | [[Category: Michaelian N]] | ||
[[Category: Patel | [[Category: Olsen RHJ]] | ||
[[Category: Roth | [[Category: Patel N]] | ||
[[Category: Stauch | [[Category: Roth BL]] | ||
[[Category: Tribo | [[Category: Stauch B]] | ||
[[Category: Weierstall | [[Category: Tribo AR]] | ||
[[Category: White | [[Category: Weierstall U]] | ||
[[Category: Zhu | [[Category: White TA]] | ||
[[Category: Zhu L]] | |||