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<StructureSection load='6ebs' size='340' side='right'caption='[[6ebs]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='6ebs' size='340' side='right'caption='[[6ebs]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ebs]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EBS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6EBS FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ebs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EBS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3tro|3tro]], [[3tjx|3tjx]], [[6dgs|6dgs]], [[6dwg|6dwg]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ebs OCA], [https://pdbe.org/6ebs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ebs RCSB], [https://www.ebi.ac.uk/pdbsum/6ebs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ebs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ebs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ebs OCA], [http://pdbe.org/6ebs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ebs RCSB], [http://www.ebi.ac.uk/pdbsum/6ebs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ebs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4QEW7_LEIMA Q4QEW7_LEIMA]
==See Also==
*[[Dihydroorotate dehydrogenase 3D structures|Dihydroorotate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hunter, W N]]
[[Category: Nonato, M C]]
[[Category: Pinheiro, M P]]
[[Category: Reis, R A.G]]
[[Category: Souza, A L.de]]
[[Category: Dihydroorotate dehydrogenase]]
[[Category: Leishmania major]]
[[Category: Leishmania major]]
[[Category: Mutant h174a]]
[[Category: Hunter WN]]
[[Category: Oxidoreductase]]
[[Category: Nonato MC]]
[[Category: Pinheiro MP]]
[[Category: Reis RAG]]
[[Category: De Souza AL]]

Latest revision as of 09:22, 11 October 2023

Crystal structure of Leishmania major dihydroorotate dehydrogenase mutant H174A in complex with orotateCrystal structure of Leishmania major dihydroorotate dehydrogenase mutant H174A in complex with orotate

Structural highlights

6ebs is a 2 chain structure with sequence from Leishmania major. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.05Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q4QEW7_LEIMA

See Also

6ebs, resolution 2.05Å

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