8b66: Difference between revisions

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-'''Unreleased structure'''
-The entry 8b66 is ON HOLD  until Paper Publication
+==Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid)==
+<StructureSection load='8b66' size='340' side='right'caption='[[8b66]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
-Authors: Hubert, L.-S., Heine, A., Klebe, G.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8b66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B66 FirstGlance]. <br>
-Description: Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid)
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.95&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4G7:3-({[2-(CARBOXYMETHOXY)-4-FLUOROBENZOYL]AMINO}METHYL)BENZOIC+ACID'>4G7</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-[[Category: Heine, A]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b66 OCA], [https://pdbe.org/8b66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b66 RCSB], [https://www.ebi.ac.uk/pdbsum/8b66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b66 ProSAT]</span></td></tr>
-[[Category: Hubert, L.-S]]
+</table>
-[[Category: Klebe, G]]
+== Function ==
+[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Heine A]]
+[[Category: Hubert L-S]]
+[[Category: Klebe G]]