5l12: Difference between revisions
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==Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase from BURKHOLDERIA PSEUDOMALLEI double mutant== | |||
<StructureSection load='5l12' size='340' side='right'caption='[[5l12]], [[Resolution|resolution]] 1.72Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5l12]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei_1106a Burkholderia pseudomallei 1106a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L12 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.716Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l12 OCA], [https://pdbe.org/5l12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l12 RCSB], [https://www.ebi.ac.uk/pdbsum/5l12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l12 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ISPF_BURP0 ISPF_BURP0] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | |||
==See Also== | |||
*[[MECDP synthase 3D structures|MECDP synthase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Burkholderia pseudomallei 1106a]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Blain JM]] | ||
[[Category: Raneiri | [[Category: Hagen TJ]] | ||
[[Category: Walter | [[Category: Horn JR]] | ||
[[Category: Raneiri G]] | |||
[[Category: Walter RL]] | |||
Latest revision as of 19:04, 4 October 2023
Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase from BURKHOLDERIA PSEUDOMALLEI double mutantCrystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase from BURKHOLDERIA PSEUDOMALLEI double mutant
Structural highlights
FunctionISPF_BURP0 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). See Also |
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