3aon: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:3aon.jpg|left|200px]]
-<!--
+==Crystal structure of the central axis (NtpD-NtpG) in the catalytic portion of Enterococcus hirae V-type sodium ATPase==
-The line below this paragraph, containing "STRUCTURE_3aon", creates the "Structure Box" on the page.
+<StructureSection load='3aon' size='340' side='right'caption='[[3aon]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[3aon]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_hirae Enterococcus hirae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AON FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-{{STRUCTURE_3aon|  PDB=3aon  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aon OCA], [https://pdbe.org/3aon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aon RCSB], [https://www.ebi.ac.uk/pdbsum/3aon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aon ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/NTPD_ENTHA NTPD_ENTHA] Involved in ATP-driven sodium extrusion.<ref>PMID:8157629</ref>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+V-ATPases function as ATP-dependent ion pumps in various membrane systems of living organisms. ATP hydrolysis causes rotation of the central rotor complex, which is composed of the central axis D subunit and a membrane c ring that are connected by F and d subunits. Here we determined the crystal structure of the DF complex of the prokaryotic V-ATPase of Enterococcus hirae at 2.0-A resolution. The structure of the D subunit comprised a long left-handed coiled coil with a unique short beta-hairpin region that is effective in stimulating the ATPase activity of V(1)-ATPase by twofold. The F subunit is bound to the middle portion of the D subunit. The C-terminal helix of the F subunit, which was believed to function as a regulatory region by extending into the catalytic A(3)B(3) complex, contributes to tight binding to the D subunit by forming a three-helix bundle. Both D and F subunits are necessary to bind the d subunit that links to the c ring. From these findings, we modeled the entire rotor complex (DFdc ring) of V-ATPase.
-===Crystal structure of the central axis (NtpD-NtpG) in the catalytic portion of Enterococcus hirae V-type sodium ATPase===
+Crystal structure of the central axis DF complex of the prokaryotic V-ATPase.,Saijo S, Arai S, Hossain KM, Yamato I, Suzuki K, Kakinuma Y, Ishizuka-Katsura Y, Ohsawa N, Terada T, Shirouzu M, Yokoyama S, Iwata S, Murata T Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):19955-60. Epub 2011 Nov 23. PMID:22114184<ref>PMID:22114184</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 3aon" style="background-color:#fffaf0;"></div>
-==About this Structure==
+==See Also==
-[[3aon]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_hirae Enterococcus hirae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AON OCA].
+*[[ATPase 3D structures|ATPase 3D structures]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Enterococcus hirae]]
-[[Category: Arai, S.]]
+[[Category: Large Structures]]
-[[Category: Hossain, K M.M.]]
+[[Category: Arai S]]
-[[Category: Ishizuka-Katsura, Y.]]
+[[Category: Hossain KMM]]
-[[Category: Iwata, S.]]
+[[Category: Ishizuka-Katsura Y]]
-[[Category: Kakinuma, Y.]]
+[[Category: Iwata S]]
-[[Category: Murata, T.]]
+[[Category: Kakinuma Y]]
-[[Category: Saijo, S.]]
+[[Category: Murata T]]
-[[Category: Shirouzu, M.]]
+[[Category: Saijo S]]
-[[Category: Terada, T.]]
+[[Category: Shirouzu M]]
-[[Category: Yamato, I.]]
+[[Category: Terada T]]
-[[Category: Yokoyama, S.]]
+[[Category: Yamato I]]
-[[Category: Alpha/beta fold]]
+[[Category: Yokoyama S]]
-[[Category: Central axis]]
-[[Category: Coiled-coil]]
-[[Category: Enterococcus]]
-[[Category: Hydrolase]]
-[[Category: Ntpa3-ntpb3]]
-[[Category: Ntpc]]
-[[Category: V-atpase]]