6cwz: Difference between revisions

<StructureSection load='6cwz' size='340' side='right'caption='[[6cwz]], [[Resolution|resolution]] 3.10&Aring;' scene=''>

<table><tr><td colspan='2'>[[6cwz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CWZ FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cwz OCA], [https://pdbe.org/6cwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cwz RCSB], [https://www.ebi.ac.uk/pdbsum/6cwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cwz ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SAE1_HUMAN SAE1_HUMAN] The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.<ref>PMID:9920803</ref> <ref>PMID:10217437</ref> <ref>PMID:10187858</ref> <ref>PMID:11481243</ref> <ref>PMID:11451954</ref> <ref>PMID:15660128</ref> <ref>PMID:20164921</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Atkison JH]]

[[Category: Lv Z]]

[[Category: Olsen SK]]

[[Category: Williams KM]]

[[Category: Yuan L]]