6cnh: Difference between revisions
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==Human PRPF4B in complex with Rebastinib== | ==Human PRPF4B in complex with Rebastinib== | ||
<StructureSection load='6cnh' size='340' side='right' caption='[[6cnh]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='6cnh' size='340' side='right'caption='[[6cnh]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CNH FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cnh OCA], [https://pdbe.org/6cnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cnh RCSB], [https://www.ebi.ac.uk/pdbsum/6cnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cnh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Arruda | [[Category: Large Structures]] | ||
[[Category: Counago | [[Category: Arruda P]] | ||
[[Category: Edwards | [[Category: Counago RM]] | ||
[[Category: Elkins | [[Category: Edwards AM]] | ||
[[Category: Fala | [[Category: Elkins JM]] | ||
[[Category: Gileadi | [[Category: Fala AM]] | ||
[[Category: Godoi | [[Category: Gileadi O]] | ||
[[Category: Guimaraes | [[Category: Godoi PHC]] | ||
[[Category: Massirer | [[Category: Guimaraes CRW]] | ||
[[Category: Ramos | [[Category: Massirer KB]] | ||
[[Category: Righetto | [[Category: Ramos PZ]] | ||
[[Category: Righetto GL]] | |||
[[Category: Salmazo | [[Category: Salmazo APT]] | ||
[[Category: Santiago | [[Category: Santiago AS]] | ||
[[Category: Silva | [[Category: Silva PNB]] | ||
Latest revision as of 18:07, 4 October 2023
Human PRPF4B in complex with RebastinibHuman PRPF4B in complex with Rebastinib
Structural highlights
FunctionPRP4B_HUMAN Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF. |
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