6cnh: Difference between revisions

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'''Unreleased structure'''


The entry 6cnh is ON HOLD
==Human PRPF4B in complex with Rebastinib==
 
<StructureSection load='6cnh' size='340' side='right'caption='[[6cnh]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
Authors: Godoi, P.H.C., Santiago, A.S., Ramos, P.Z., Silva, P.N.B., Righetto, G.L., Guimaraes, C., Massirer, K.B., Arruda, P., Elkins, J.M., Edwards, A.M., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6cnh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CNH FirstGlance]. <br>
Description: Human PRPF4B in complex with Rebastinib
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=919:4-[4-({[3-TERT-BUTYL-1-(QUINOLIN-6-YL)-1H-PYRAZOL-5-YL]CARBAMOYL}AMINO)-3-FLUOROPHENOXY]-N-METHYLPYRIDINE-2-CARBOXAMIDE'>919</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Righetto, G.L]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cnh OCA], [https://pdbe.org/6cnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cnh RCSB], [https://www.ebi.ac.uk/pdbsum/6cnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cnh ProSAT]</span></td></tr>
[[Category: Elkins, J.M]]
</table>
[[Category: Massirer, K.B]]
== Function ==
[[Category: Guimaraes, C]]
[https://www.uniprot.org/uniprot/PRP4B_HUMAN PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
[[Category: Edwards, A.M]]
__TOC__
[[Category: Silva, P.N.B]]
</StructureSection>
[[Category: Arruda, P]]
[[Category: Homo sapiens]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Large Structures]]
[[Category: Santiago, A.S]]
[[Category: Arruda P]]
[[Category: Ramos, P.Z]]
[[Category: Counago RM]]
[[Category: Godoi, P.H.C]]
[[Category: Edwards AM]]
[[Category: Elkins JM]]
[[Category: Fala AM]]
[[Category: Gileadi O]]
[[Category: Godoi PHC]]
[[Category: Guimaraes CRW]]
[[Category: Massirer KB]]
[[Category: Ramos PZ]]
[[Category: Righetto GL]]
[[Category: Salmazo APT]]
[[Category: Santiago AS]]
[[Category: Silva PNB]]

Latest revision as of 18:07, 4 October 2023

Human PRPF4B in complex with RebastinibHuman PRPF4B in complex with Rebastinib

Structural highlights

6cnh is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PRP4B_HUMAN Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

6cnh, resolution 2.00Å

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OCA
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