5w06: Difference between revisions

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==HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587==
==HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587==
<StructureSection load='5w06' size='340' side='right' caption='[[5w06]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5w06' size='340' side='right'caption='[[5w06]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5w06]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5W06 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5w06]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W06 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4m7k|4m7k]], [[4m7l|4m7l]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">F3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w06 OCA], [https://pdbe.org/5w06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w06 RCSB], [https://www.ebi.ac.uk/pdbsum/5w06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w06 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5w06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w06 OCA], [http://pdbe.org/5w06 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5w06 RCSB], [http://www.ebi.ac.uk/pdbsum/5w06 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5w06 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TF_HUMAN TF_HUMAN]] Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<ref>PMID:12652293</ref>
[https://www.uniprot.org/uniprot/TF_HUMAN TF_HUMAN] Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.<ref>PMID:12652293</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5w06" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5w06" style="background-color:#fffaf0;"></div>
==See Also==
*[[Tissue factor|Tissue factor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Gilliland, G L]]
[[Category: Mus musculus]]
[[Category: Malia, T J]]
[[Category: Gilliland GL]]
[[Category: Obmolova, G]]
[[Category: Malia TJ]]
[[Category: Teplyakov, A]]
[[Category: Obmolova G]]
[[Category: Immune system]]
[[Category: Teplyakov A]]

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