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==Kaposi's Sarcoma Herpesvirus Protease in Complex with Allosteric Inhibitor==
==Kaposi's Sarcoma Herpesvirus Protease in Complex with Allosteric Inhibitor==
<StructureSection load='5uv3' size='340' side='right' caption='[[5uv3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='5uv3' size='340' side='right'caption='[[5uv3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5uv3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UV3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5uv3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UV3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8N4:4-{[6-(CYCLOHEXYLMETHYL)PYRIDINE-2-CARBONYL]AMINO}-3-{[3-(TRIFLUOROMETHOXY)PHENYL]AMINO}BENZOIC+ACID'>8N4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ur3|5ur3]], [[5ute|5ute]], [[5utn|5utn]], [[5uvp|5uvp]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8N4:4-{[6-(CYCLOHEXYLMETHYL)PYRIDINE-2-CARBONYL]AMINO}-3-{[3-(TRIFLUOROMETHOXY)PHENYL]AMINO}BENZOIC+ACID'>8N4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uv3 OCA], [http://pdbe.org/5uv3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uv3 RCSB], [http://www.ebi.ac.uk/pdbsum/5uv3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uv3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5uv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uv3 OCA], [https://pdbe.org/5uv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5uv3 RCSB], [https://www.ebi.ac.uk/pdbsum/5uv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5uv3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O40922_HHV8 O40922_HHV8]
==See Also==
*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acker, T M]]
[[Category: Human gammaherpesvirus 8]]
[[Category: Bohn, M F]]
[[Category: Large Structures]]
[[Category: Craik, C S]]
[[Category: Acker TM]]
[[Category: Gable, J]]
[[Category: Bohn M-F]]
[[Category: Capsid maturation]]
[[Category: Craik CS]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Gable J]]
[[Category: Serine hydrolase]]
[[Category: Viral protein]]

Latest revision as of 16:35, 4 October 2023

Kaposi's Sarcoma Herpesvirus Protease in Complex with Allosteric InhibitorKaposi's Sarcoma Herpesvirus Protease in Complex with Allosteric Inhibitor

Structural highlights

5uv3 is a 2 chain structure with sequence from Human gammaherpesvirus 8. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.95Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O40922_HHV8

See Also

5uv3, resolution 1.95Å

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