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==Class II fructose-1,6-bisphosphate aldolase H180Q variant of Helicobacter pylori with FBP==
==Class II fructose-1,6-bisphosphate aldolase H180Q variant of Helicobacter pylori with FBP==
<StructureSection load='5ud3' size='340' side='right' caption='[[5ud3]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
<StructureSection load='5ud3' size='340' side='right'caption='[[5ud3]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ud3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UD3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UD3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ud3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UD3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UD3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P6F:1,6-DI-O-PHOSPHONO-D-FRUCTOSE'>P6F</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.44&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uck|5uck]], [[5ucn|5ucn]], [[5ucp|5ucp]], [[5ucs|5ucs]], [[5ucz|5ucz]], [[5ud0|5ud0]], [[5ud1|5ud1]], [[5ud2|5ud2]], [[5ud4|5ud4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P6F:1,6-DI-O-PHOSPHONO-D-FRUCTOSE'>P6F</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ud3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ud3 OCA], [https://pdbe.org/5ud3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ud3 RCSB], [https://www.ebi.ac.uk/pdbsum/5ud3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ud3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ud3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ud3 OCA], [http://pdbe.org/5ud3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ud3 RCSB], [http://www.ebi.ac.uk/pdbsum/5ud3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ud3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ALF_HELPY ALF_HELPY]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).  
[https://www.uniprot.org/uniprot/ALF_HELPY ALF_HELPY] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
*[[Aldolase 3D structures|Aldolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fructose-bisphosphate aldolase]]
[[Category: Helicobacter pylori 26695]]
[[Category: Jacques, B]]
[[Category: Large Structures]]
[[Category: Sygusch, J]]
[[Category: Jacques B]]
[[Category: Glycolysis]]
[[Category: Sygusch J]]
[[Category: Lyase]]
[[Category: Metalloenzyme]]

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