5t4j: Difference between revisions

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<StructureSection load='5t4j' size='340' side='right'caption='[[5t4j]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
<StructureSection load='5t4j' size='340' side='right'caption='[[5t4j]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5t4j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T4J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T4J FirstGlance]. <br>
<table><tr><td colspan='2'>[[5t4j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T4J FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.231&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gabR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t4j OCA], [http://pdbe.org/5t4j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t4j RCSB], [http://www.ebi.ac.uk/pdbsum/5t4j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t4j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t4j OCA], [https://pdbe.org/5t4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t4j RCSB], [https://www.ebi.ac.uk/pdbsum/5t4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t4j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GABR_BACSU GABR_BACSU]] Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate.<ref>PMID:12123465</ref> <ref>PMID:15223311</ref>
[https://www.uniprot.org/uniprot/GABR_BACSU GABR_BACSU] Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate.<ref>PMID:12123465</ref> <ref>PMID:15223311</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<div class="pdbe-citations 5t4j" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5t4j" style="background-color:#fffaf0;"></div>
==See Also==
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Vibrio subtilis ehrenberg 1835]]
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Belitsky, B R]]
[[Category: Belitsky BR]]
[[Category: Farley, M]]
[[Category: Farley M]]
[[Category: Juncosa, J I]]
[[Category: Juncosa JI]]
[[Category: Le, H V]]
[[Category: Le HV]]
[[Category: Lehrer, H J.S]]
[[Category: Lehrer HJS]]
[[Category: Liu, D]]
[[Category: Liu D]]
[[Category: Petsko, G A]]
[[Category: Petsko GA]]
[[Category: Ringe, D]]
[[Category: Ringe D]]
[[Category: Sanishvili, R]]
[[Category: Sanishvili R]]
[[Category: Silverman, R B]]
[[Category: Silverman RB]]
[[Category: Wu, R]]
[[Category: Wu R]]
[[Category: External aldimine]]
[[Category: Gaba]]
[[Category: Gabr]]
[[Category: Mocr]]
[[Category: Plp]]
[[Category: Transcription regulator]]

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