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==Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in complex with cyclopamine==
==Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in complex with cyclopamine==
<StructureSection load='5kzy' size='340' side='right' caption='[[5kzy]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
<StructureSection load='5kzy' size='340' side='right'caption='[[5kzy]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5kzy]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KZY FirstGlance]. <br>
<table><tr><td colspan='2'>[[5kzy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KZY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CY8:CYCLOPAMINE'>CY8</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.484&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kzv|5kzv]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CY8:CYCLOPAMINE'>CY8</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kzy OCA], [http://pdbe.org/5kzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kzy RCSB], [http://www.ebi.ac.uk/pdbsum/5kzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kzy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kzy OCA], [https://pdbe.org/5kzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kzy RCSB], [https://www.ebi.ac.uk/pdbsum/5kzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kzy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q98SW5_XENLA Q98SW5_XENLA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Huang, P]]
[[Category: Large Structures]]
[[Category: Kim, Y]]
[[Category: Xenopus laevis]]
[[Category: Salic, A]]
[[Category: Huang P]]
[[Category: Cysteine-rich domain]]
[[Category: Kim Y]]
[[Category: Gpcr]]
[[Category: Salic A]]
[[Category: Hedgehog signaling]]
[[Category: Signaling protein]]
[[Category: Sterol]]

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