5kns: Difference between revisions

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-'''Unreleased structure'''
-The entry 5kns is ON HOLD
+==E coli hypoxanthine guanine phosphoribosyltransferase in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]hypoxanthine==
+<StructureSection load='5kns' size='340' side='right'caption='[[5kns]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5kns]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNS FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.792&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3L7:(2-{[2-(6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)ETHYL](2-{[(E)-2-PHOSPHONOETHENYL]OXY}ETHYL)AMINO}ETHYL)PHOSPHONIC+ACID'>3L7</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kns OCA], [https://pdbe.org/5kns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kns RCSB], [https://www.ebi.ac.uk/pdbsum/5kns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kns ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HPRT_ECOLI HPRT_ECOLI] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine.
-Authors: Eng, W.S., Keough, D.T., Hockova, D., Janeba, Z.
+==See Also==
+*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
-Description: E coli hypoxanthine guanine phosphoribosyltransferase in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]hypoxanthine
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Eng, W.S]]
+[[Category: Escherichia coli]]
-[[Category: Keough, D.T]]
+[[Category: Large Structures]]
-[[Category: Hockova, D]]
+[[Category: Eng WS]]
-[[Category: Janeba, Z]]
+[[Category: Hockova D]]
+[[Category: Janeba Z]]
+[[Category: Keough DT]]