8slu: Difference between revisions
No edit summary |
No edit summary |
||
(One intermediate revision by the same user not shown) | |||
Line 1: | Line 1: | ||
==Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa)== | |||
<StructureSection load='8slu' size='340' side='right'caption='[[8slu]], [[Resolution|resolution]] 1.84Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8slu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SLU FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8slu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8slu OCA], [https://pdbe.org/8slu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8slu RCSB], [https://www.ebi.ac.uk/pdbsum/8slu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8slu ProSAT]</span></td></tr> | ||
[[Category: Ebrahim | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/PTN5_HUMAN PTN5_HUMAN] May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.<ref>PMID:21777200</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: Kim | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ebrahim A]] | |||
[[Category: Finke AD]] | |||
[[Category: Guerrero L]] | |||
[[Category: Huang Q]] | |||
[[Category: Keedy DA]] | |||
[[Category: Kim M]] | |||
[[Category: Riley BT]] |