5knu: Difference between revisions

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-'''Unreleased structure'''
-The entry 5knu is ON HOLD
+==Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 9-[N,N-(Bis-3-phosphonopropyl)aminomethyl]-9-deazahypoxanthine==
+<StructureSection load='5knu' size='340' side='right'caption='[[5knu]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5knu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNU FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.808&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6WA:3-[(4-oxidanylidene-3,5-dihydropyrrolo[3,2-d]pyrimidin-7-yl)methyl-(3-phosphonopropyl)amino]propylphosphonic+acid'>6WA</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5knu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knu OCA], [https://pdbe.org/5knu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5knu RCSB], [https://www.ebi.ac.uk/pdbsum/5knu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5knu ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/HPRT_ECOLI HPRT_ECOLI] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine.
-Authors: Eng, W.S., Keough, D.T., Baszczynski, O., Hockova, D., Janeba, Z.
+==See Also==
+*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
-Description: Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 9-[N,N-(Bis-3-phosphonopropyl)aminomethyl]-9-deazahypoxanthine
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Eng, W.S]]
+[[Category: Escherichia coli]]
-[[Category: Keough, D.T]]
+[[Category: Large Structures]]
-[[Category: Hockova, D]]
+[[Category: Baszczynski O]]
-[[Category: Janeba, Z]]
+[[Category: Eng WS]]
-[[Category: Baszczynski, O]]
+[[Category: Hockova D]]
+[[Category: Janeba Z]]
+[[Category: Keough DT]]