5knr: Difference between revisions

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 ==E. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanine==
-<StructureSection load='5knr' size='340' side='right' caption='[[5knr]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
+<StructureSection load='5knr' size='340' side='right'caption='[[5knr]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5knr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KNR FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5knr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNR FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3L5:(2-{[2-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)ETHYL][2-(2-PHOSPHONOETHOXY)ETHYL]AMINO}ETHYL)PHOSPHONIC+ACID'>3L5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.864&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5knp|5knp]], [[5knq|5knq]], [[5kny|5kny]], [[5kns|5kns]], [[5knv|5knv]], [[5knu|5knu]], [[5knt|5knt]], [[5knx|5knx]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3L5:(2-{[2-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)ETHYL][2-(2-PHOSPHONOETHOXY)ETHYL]AMINO}ETHYL)PHOSPHONIC+ACID'>3L5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5knr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knr OCA], [http://pdbe.org/5knr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knr RCSB], [http://www.ebi.ac.uk/pdbsum/5knr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knr ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5knr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knr OCA], [https://pdbe.org/5knr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5knr RCSB], [https://www.ebi.ac.uk/pdbsum/5knr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5knr ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/HPRT_ECOLI HPRT_ECOLI] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine.
+==See Also==
+*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
 __TOC__
 </StructureSection>
-[[Category: Eng, W S]]
+[[Category: Escherichia coli]]
-[[Category: Hockova, D]]
+[[Category: Large Structures]]
-[[Category: Janeba, Z]]
+[[Category: Eng WS]]
-[[Category: Keough, D T]]
+[[Category: Hockova D]]
-[[Category: Complex]]
+[[Category: Janeba Z]]
-[[Category: Inhibitor]]
+[[Category: Keough DT]]
-[[Category: Phosphoribosyltransferase]]
-[[Category: Transferase-inhibitor complex]]