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==Crystal structure of iron-sulfur cluster containing photolyase PhrB mutant I51W==
==Crystal structure of iron-sulfur cluster containing photolyase PhrB mutant I51W==
<StructureSection load='5kcm' size='340' side='right' caption='[[5kcm]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='5kcm' size='340' side='right'caption='[[5kcm]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5kcm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KCM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KCM FirstGlance]. <br>
<table><tr><td colspan='2'>[[5kcm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_fabrum_str._C58 Agrobacterium fabrum str. C58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KCM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.149&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(6-4)DNA_photolyase (6-4)DNA photolyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.99.13 4.1.99.13] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kcm OCA], [http://pdbe.org/5kcm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kcm RCSB], [http://www.ebi.ac.uk/pdbsum/5kcm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kcm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kcm OCA], [https://pdbe.org/5kcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kcm RCSB], [https://www.ebi.ac.uk/pdbsum/5kcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kcm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PHRB_AGRFC PHRB_AGRFC]] Photolyase involved in the repair of UV-induced (6-4) lesions in DNA. Catalyzes the photoreactivation of (6-4) pyrimidine-pyrimidone photoproducts by using blue-light energy. Can repair (6-4) photoproducts in ssDNA as well as in dsDNA.<ref>PMID:23589886</ref>
[https://www.uniprot.org/uniprot/PHRB_AGRFC PHRB_AGRFC] Photolyase involved in the repair of UV-induced (6-4) lesions in DNA. Catalyzes the photoreactivation of (6-4) pyrimidine-pyrimidone photoproducts by using blue-light energy. Can repair (6-4) photoproducts in ssDNA as well as in dsDNA.<ref>PMID:23589886</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bowatte, K]]
[[Category: Agrobacterium fabrum str. C58]]
[[Category: Lamparter, T]]
[[Category: Large Structures]]
[[Category: Yang, X]]
[[Category: Bowatte K]]
[[Category: Zhang, F]]
[[Category: Lamparter T]]
[[Category: Fes-bcp]]
[[Category: Yang X]]
[[Category: Lyase]]
[[Category: Zhang F]]
[[Category: Mutant]]

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