5cu9: Difference between revisions

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<StructureSection load='5cu9' size='340' side='right'caption='[[5cu9]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
<StructureSection load='5cu9' size='340' side='right'caption='[[5cu9]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5cu9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Canal Canal]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CU9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5cu9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CU9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n3t|4n3t]], [[4n3u|4n3u]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SOD5, PGA3, SOD31, CaO19.2060, CaO19.9607 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=237561 CANAL])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cu9 OCA], [https://pdbe.org/5cu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cu9 RCSB], [https://www.ebi.ac.uk/pdbsum/5cu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cu9 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cu9 OCA], [http://pdbe.org/5cu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cu9 RCSB], [http://www.ebi.ac.uk/pdbsum/5cu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cu9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SOD5_CANAL SOD5_CANAL]] Superoxide dismutases serve to convert damaging superoxide radicals, a key form of ROS, to less damaging hydrogen peroxide that can be converted into water by catalase action. Degrades host-derived reactive oxygen species to escape innate immune surveillance. Involved in the occurrence of miconazole-tolerant persisters in biofilms. Persisters are cells that survive high doses of an antimicrobial agent.<ref>PMID:14617819</ref> <ref>PMID:19019164</ref> <ref>PMID:21746956</ref>
[https://www.uniprot.org/uniprot/SOD5_CANAL SOD5_CANAL] Superoxide dismutases serve to convert damaging superoxide radicals, a key form of ROS, to less damaging hydrogen peroxide that can be converted into water by catalase action. Degrades host-derived reactive oxygen species to escape innate immune surveillance. Involved in the occurrence of miconazole-tolerant persisters in biofilms. Persisters are cells that survive high doses of an antimicrobial agent.<ref>PMID:14617819</ref> <ref>PMID:19019164</ref> <ref>PMID:21746956</ref>  


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Canal]]
[[Category: Candida albicans SC5314]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Superoxide dismutase]]
[[Category: Galaleldeen A]]
[[Category: Galaleldeen, A]]
[[Category: Hart PJ]]
[[Category: Hart, P J]]
[[Category: Taylor AB]]
[[Category: Taylor, A B]]
[[Category: Waninger-Saroni JJ]]
[[Category: Waninger-Saroni, J J]]
[[Category: Antioxidant]]
[[Category: Disulfide bond]]
[[Category: Extracellular]]
[[Category: Oxidative burst]]
[[Category: Oxidoreductase]]
[[Category: Zinc loop]]

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