5cc3: Difference between revisions
New page: '''Unreleased structure''' The entry 5cc3 is ON HOLD Authors: Huang, H.-L., Sacchettini, J.C. Description: Crystal structure of Mycobacterium tuberculosis malate synthase in complex wi... |
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==Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 6-bromo-1H-indole-2-carboxylic acid== | |||
<StructureSection load='5cc3' size='340' side='right'caption='[[5cc3]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5cc3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CC3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.204Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4ZU:6-BROMANYL-1H-INDOLE-2-CARBOXYLIC+ACID'>4ZU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cc3 OCA], [https://pdbe.org/5cc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cc3 RCSB], [https://www.ebi.ac.uk/pdbsum/5cc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cc3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MASZ_MYCTU MASZ_MYCTU] Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA (By similarity).[HAMAP-Rule:MF_00641] | |||
==See Also== | |||
*[[Malate synthase 3D structures|Malate synthase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Huang | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Huang H-L]] | |||
[[Category: Sacchettini JC]] |