4zt6: Difference between revisions

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 ==Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-3,4-dihydro-2H-chromen-4-yl]-N'-(5-fluoro-1H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1709)==
-<StructureSection load='4zt6' size='340' side='right' caption='[[4zt6]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
+<StructureSection load='4zt6' size='340' side='right'caption='[[4zt6]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4zt6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZT6 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4zt6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZT6 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4RD:N-[(4R)-6,8-DICHLORO-3,4-DIHYDRO-2H-CHROMEN-4-YL]-N-(5-FLUORO-1H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PROPANE-1,3-DIAMINE'>4RD</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4RD:N-[(4R)-6,8-DICHLORO-3,4-DIHYDRO-2H-CHROMEN-4-YL]-N-(5-FLUORO-1H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PROPANE-1,3-DIAMINE'>4RD</scene>, <scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zt7|4zt7]], [[4zt5|4zt5]], [[4zt4|4zt4]], [[4zt3|4zt3]], [[4zt2|4zt2]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zt6 OCA], [https://pdbe.org/4zt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zt6 RCSB], [https://www.ebi.ac.uk/pdbsum/4zt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zt6 ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zt6 OCA], [http://pdbe.org/4zt6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zt6 RCSB], [http://www.ebi.ac.uk/pdbsum/4zt6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zt6 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q38C91_TRYB2 Q38C91_TRYB2]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 19: / Line 19: @@
 </div>
 <div class="pdbe-citations 4zt6" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Methionine--tRNA ligase]]
+[[Category: Large Structures]]
-[[Category: Hol, W G.J]]
+[[Category: Trypanosoma brucei brucei TREU927]]
-[[Category: Koh, C Y]]
+[[Category: Hol WGJ]]
-[[Category: Aar]]
+[[Category: Koh C-Y]]
-[[Category: Aminoacyl-trna synthetase]]
-[[Category: Ligase]]
-[[Category: Ligase-ligase inhibitor complex]]
-[[Category: Metr]]
-[[Category: Protein-inhibitor complex]]
-[[Category: Trypanosoma brucei]]