4zok: Difference between revisions

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-'''Unreleased structure'''
-The entry 4zok is ON HOLD
+==Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)==
+<StructureSection load='4zok' size='340' side='right'caption='[[4zok]], [[Resolution|resolution]] 2.34&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4zok]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZOK FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.34&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=62L:4-METHYL-2-{[2-METHYL-6-(METHYLSULFONYL)PHENYL]AMINO}BENZOIC+ACID'>62L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zok OCA], [https://pdbe.org/4zok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zok RCSB], [https://www.ebi.ac.uk/pdbsum/4zok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zok ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
-Authors: Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC)
+==See Also==
+*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
-Description:
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Lott, J.S]]
+[[Category: Large Structures]]
-[[Category: Evans, G.L]]
+[[Category: Mycobacterium tuberculosis H37Ra]]
-[[Category: Baker, E.N]]
+[[Category: Baker EN]]
-[[Category: Tb Structural Genomics Consortium (Tbsgc)]]
+[[Category: Evans GL]]
+[[Category: Lott JS]]