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==Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein (LsAChBP) in Complex with 3-Pyrrolylmethylene Anabaseine==
==Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein (LsAChBP) in Complex with 3-Pyrrolylmethylene Anabaseine==
<StructureSection load='4zk1' size='340' side='right' caption='[[4zk1]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='4zk1' size='340' side='right'caption='[[4zk1]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zk1]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZK1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZK1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zk1]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZK1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZK1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4P7:(3E)-3-(1H-PYRROL-3-YLMETHYLIDENE)-3,4,5,6-TETRAHYDRO-2,3-BIPYRIDINE'>4P7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zjt|4zjt]], [[4zk4|4zk4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4P7:(3E)-3-(1H-PYRROL-3-YLMETHYLIDENE)-3,4,5,6-TETRAHYDRO-2,3-BIPYRIDINE'>4P7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zk1 OCA], [http://pdbe.org/4zk1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zk1 RCSB], [http://www.ebi.ac.uk/pdbsum/4zk1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zk1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zk1 OCA], [https://pdbe.org/4zk1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zk1 RCSB], [https://www.ebi.ac.uk/pdbsum/4zk1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zk1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.  
[https://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST] Binds to acetylcholine. Modulates neuronal synaptic transmission.


==See Also==
==See Also==
*[[Acetylcholine binding protein|Acetylcholine binding protein]]
*[[Acetylcholine binding protein 3D structures|Acetylcholine binding protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bobango, J]]
[[Category: Large Structures]]
[[Category: Talley, T T]]
[[Category: Lymnaea stagnalis]]
[[Category: Wu, J]]
[[Category: Bobango J]]
[[Category: Achbp]]
[[Category: Talley TT]]
[[Category: Anabaseine]]
[[Category: Wu J]]
[[Category: Nicotinic]]
[[Category: Receptor]]

Latest revision as of 11:19, 27 September 2023

Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein (LsAChBP) in Complex with 3-Pyrrolylmethylene AnabaseineCrystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein (LsAChBP) in Complex with 3-Pyrrolylmethylene Anabaseine

Structural highlights

4zk1 is a 10 chain structure with sequence from Lymnaea stagnalis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.75Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ACHP_LYMST Binds to acetylcholine. Modulates neuronal synaptic transmission.

See Also

4zk1, resolution 1.75Å

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