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==HipB-O3 20mer complex==
==HipB-O3 20mer complex==
<StructureSection load='4z58' size='340' side='right' caption='[[4z58]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4z58' size='340' side='right'caption='[[4z58]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4z58]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z58 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z58 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4z58]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z58 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4z5a|4z5a]], [[4z5b|4z5b]], [[4z5c|4z5c]], [[4z5d|4z5d]], [[4z5e|4z5e]], [[4z5f|4z5f]], [[4z5g|4z5g]], [[4z5h|4z5h]], [[4z5i|4z5i]], [[4z5j|4z5j]], [[4z5k|4z5k]], [[4z5l|4z5l]], [[4z5m|4z5m]], [[4z5n|4z5n]], [[4z5o|4z5o]], [[4z52|4z52]], [[4z56|4z56]], [[4z57|4z57]], [[4z59|4z59]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hipB, b1508, JW1501 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z58 OCA], [https://pdbe.org/4z58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z58 RCSB], [https://www.ebi.ac.uk/pdbsum/4z58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z58 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z58 OCA], [http://pdbe.org/4z58 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z58 RCSB], [http://www.ebi.ac.uk/pdbsum/4z58 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4z58 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HIPB_ECOLI HIPB_ECOLI]] Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the toxic effect of cognate toxin HipA. Binds to operator sites with the consensus sequence 5-'TATCCN(8)GGATA-3' to repress the hipBA operon promoter.  
[https://www.uniprot.org/uniprot/HIPB_ECOLI HIPB_ECOLI] Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the toxic effect of cognate toxin HipA. Binds to operator sites with the consensus sequence 5-'TATCCN(8)GGATA-3' to repress the hipBA operon promoter.
 
==See Also==
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Brennan, R G]]
[[Category: Large Structures]]
[[Category: Min, J]]
[[Category: Synthetic construct]]
[[Category: Schumacher, M A]]
[[Category: Brennan RG]]
[[Category: Hipa sequestering]]
[[Category: Min J]]
[[Category: Hth motif]]
[[Category: Schumacher MA]]
[[Category: Transcription repressor]]
[[Category: Transcription-dna complex]]

Latest revision as of 11:12, 27 September 2023

HipB-O3 20mer complexHipB-O3 20mer complex

Structural highlights

4z58 is a 2 chain structure with sequence from Escherichia coli K-12 and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HIPB_ECOLI Antitoxin component of a toxin-antitoxin (TA) module. Neutralizes the toxic effect of cognate toxin HipA. Binds to operator sites with the consensus sequence 5-'TATCCN(8)GGATA-3' to repress the hipBA operon promoter.

See Also

4z58, resolution 2.50Å

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