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==Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid and oxalic acid==
==Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid and oxalic acid==
<StructureSection load='4ywb' size='340' side='right' caption='[[4ywb]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4ywb' size='340' side='right'caption='[[4ywb]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ywb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YWB FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ywb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YWB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1WD:3-SULFANYLPYRIDINE-2-CARBOXYLIC+ACID'>1WD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OXD:OXALIC+ACID'>OXD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yw8|4yw8]], [[4yw9|4yw9]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1WD:3-SULFANYLPYRIDINE-2-CARBOXYLIC+ACID'>1WD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OXD:OXALIC+ACID'>OXD</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ywb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ywb OCA], [https://pdbe.org/4ywb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ywb RCSB], [https://www.ebi.ac.uk/pdbsum/4ywb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ywb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ywb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ywb OCA], [http://pdbe.org/4ywb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ywb RCSB], [http://www.ebi.ac.uk/pdbsum/4ywb PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PCKGC_RAT PCKGC_RAT]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.  
[https://www.uniprot.org/uniprot/PCKGC_RAT PCKGC_RAT] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4ywb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4ywb" style="background-color:#fffaf0;"></div>
==See Also==
*[[Phosphoenolpyruvate carboxykinase 3D structures|Phosphoenolpyruvate carboxykinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Balan, M D]]
[[Category: Large Structures]]
[[Category: Holyoak, T]]
[[Category: Rattus norvegicus]]
[[Category: Johnson, T A]]
[[Category: Balan MD]]
[[Category: Lotosky, W R]]
[[Category: Holyoak T]]
[[Category: Mcleod, M J]]
[[Category: Johnson TA]]
[[Category: Gluconeogenesis]]
[[Category: Lotosky WR]]
[[Category: Kinase]]
[[Category: Mcleod MJ]]
[[Category: Lyase]]

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