4y2d: Difference between revisions

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==Crystal structure of the mCD1d/7DW8-5/iNKTCR ternary complex==
==Crystal structure of the mCD1d/7DW8-5/iNKTCR ternary complex==
<StructureSection load='4y2d' size='340' side='right' caption='[[4y2d]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
<StructureSection load='4y2d' size='340' side='right'caption='[[4y2d]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4y2d]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y2D FirstGlance]. <br>
<table><tr><td colspan='2'>[[4y2d]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y2D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y2D FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7DW:11-(4-FLUOROPHENYL)-N-[(2S,3S,4R)-1-(ALPHA-D-GALACTOPYRANOSYLOXY)-3,4-DIHYDROXYOCTADECAN-2-YL]UNDECANAMIDE'>7DW</scene>, <scene name='pdbligand=FU4:2,6-ANHYDRO-1-DEOXY-D-GALACTITOL'>FU4</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y16|4y16]], [[4y4f|4y4f]], [[4y4h|4y4h]], [[4y4k|4y4k]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7DW:11-(4-FLUOROPHENYL)-N-[(2S,3S,4R)-1-(ALPHA-D-GALACTOPYRANOSYLOXY)-3,4-DIHYDROXYOCTADECAN-2-YL]UNDECANAMIDE'>7DW</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y2d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4y2d RCSB], [http://www.ebi.ac.uk/pdbsum/4y2d PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y2d OCA], [https://pdbe.org/4y2d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y2d RCSB], [https://www.ebi.ac.uk/pdbsum/4y2d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y2d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE]] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref> [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
[https://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref>  
 
==See Also==
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Yu, E D]]
[[Category: Homo sapiens]]
[[Category: Zajonc, D M]]
[[Category: Large Structures]]
[[Category: Glycolipid antigen presentation]]
[[Category: Mus musculus]]
[[Category: Ig-fold]]
[[Category: Yu ED]]
[[Category: Immune system]]
[[Category: Zajonc DM]]
[[Category: Mhc-fold]]
[[Category: T cell receptor]]

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