4xk4: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4xk4 is ON HOLD
+==E. coli transcriptional regulator RUTR with dihydrouracil==
+<StructureSection load='4xk4' size='340' side='right'caption='[[4xk4]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xk4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XK4 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DUC:DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE'>DUC</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xk4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xk4 OCA], [https://pdbe.org/4xk4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xk4 RCSB], [https://www.ebi.ac.uk/pdbsum/4xk4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xk4 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RUTR_ECOLI RUTR_ECOLI] Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX).<ref>PMID:16540542</ref> <ref>PMID:17919280</ref>
-Authors: Shumilin, I.A., Cooper, D.R., Shabalin, I.G., Grabowski, M., Almo, S.C., Minor, W., New York Structural Genomics Research Consortium (NYSGRC)
+==See Also==
+*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
-Description: E. COLI TRANSCRIPTIONAL REGULATOR RUTR WITH DIHYDROURACIL
+*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
-[[Category: Unreleased Structures]]
+== References ==
-[[Category: Almo, S.C]]
+<references/>
-[[Category: Shumilin, I.A]]
+__TOC__
-[[Category: Minor, W]]
+</StructureSection>
-[[Category: Shabalin, I.G]]
+[[Category: Escherichia coli K-12]]
-[[Category: New York Structural Genomics Research Consortium (Nysgrc)]]
+[[Category: Large Structures]]
-[[Category: Grabowski, M]]
+[[Category: Almo SC]]
-[[Category: Cooper, D.R]]
+[[Category: Cooper DR]]
+[[Category: Grabowski M]]
+[[Category: Minor W]]
+[[Category: Shabalin IG]]
+[[Category: Shumilin IA]]