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==Crystal structure of Pseudomonas aeruginosa PBP3 with a R4 substituted vinyl monocarbam==
==Crystal structure of Pseudomonas aeruginosa PBP3 with a R4 substituted vinyl monocarbam==
<StructureSection load='4wek' size='340' side='right' caption='[[4wek]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
<StructureSection load='4wek' size='340' side='right'caption='[[4wek]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4wek]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WEK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WEK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4wek]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_ATCC_14886 Pseudomonas aeruginosa ATCC 14886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WEK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WEK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3LC:(3S,4S,7Z)-7-(2-AMINO-1,3-THIAZOL-4-YL)-3-ETHENYL-4-FORMYL-1-[({3-(5-HYDROXY-4-OXO-3,4-DIHYDROPYRIDIN-2-YL)-4-[3-(METHYLSULFONYL)PROPYL]-5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-1-YL}SULFONYL)AMINO]-10,10-DIMETHYL-1,6-DIOXO-9-OXA-2,5,8-TRIAZAUNDEC-7-EN-11-OIC+ACID'>3LC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wej|4wej]], [[4wel|4wel]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3LC:(3S,4S,7Z)-7-(2-AMINO-1,3-THIAZOL-4-YL)-3-ETHENYL-4-FORMYL-1-[({3-(5-HYDROXY-4-OXO-3,4-DIHYDROPYRIDIN-2-YL)-4-[3-(METHYLSULFONYL)PROPYL]-5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-1-YL}SULFONYL)AMINO]-10,10-DIMETHYL-1,6-DIOXO-9-OXA-2,5,8-TRIAZAUNDEC-7-EN-11-OIC+ACID'>3LC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wek OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wek RCSB], [http://www.ebi.ac.uk/pdbsum/4wek PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wek OCA], [https://pdbe.org/4wek PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wek RCSB], [https://www.ebi.ac.uk/pdbsum/4wek PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wek ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0M3KKZ4_PSEAI A0A0M3KKZ4_PSEAI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4wek" style="background-color:#fffaf0;"></div>
==See Also==
*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ferguson, A D]]
[[Category: Large Structures]]
[[Category: Inhibitor]]
[[Category: Pseudomonas aeruginosa ATCC 14886]]
[[Category: Penicillin-binding protein 3]]
[[Category: Ferguson AD]]
[[Category: Penicillin-binding protein-inhibitor complex]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Siderophore-conjugated monocarbam]]

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