4pe8: Difference between revisions

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==Crystal structure of TatD in complex with trinucleotide DNA==
==Crystal structure of TatD in complex with trinucleotide DNA==
<StructureSection load='4pe8' size='340' side='right' caption='[[4pe8]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
<StructureSection load='4pe8' size='340' side='right'caption='[[4pe8]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pe8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PE8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PE8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pe8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PE8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PE8 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p5u|4p5u]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.894&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tatD, mttC, yigW, yigX, b4483, JW5931 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pe8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pe8 OCA], [https://pdbe.org/4pe8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pe8 RCSB], [https://www.ebi.ac.uk/pdbsum/4pe8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pe8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pe8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pe8 OCA], [http://pdbe.org/4pe8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pe8 RCSB], [http://www.ebi.ac.uk/pdbsum/4pe8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pe8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TATD_ECOLI TATD_ECOLI]] Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Although TatD is not required for export activity, it is a central component of a quality control system that is linked to the Tat translocation system. May act by degrading wild-type pre-protein molecules that are misfolded. Shows magnesium-dependent DNase activity.<ref>PMID:10747959</ref> <ref>PMID:19343049</ref>
[https://www.uniprot.org/uniprot/TATD_ECOLI TATD_ECOLI] Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Although TatD is not required for export activity, it is a central component of a quality control system that is linked to the Tat translocation system. May act by degrading wild-type pre-protein molecules that are misfolded. Shows magnesium-dependent DNase activity.<ref>PMID:10747959</ref> <ref>PMID:19343049</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Chen, Y]]
[[Category: Large Structures]]
[[Category: Duh, Y]]
[[Category: Synthetic construct]]
[[Category: Hsiao, Y Y]]
[[Category: Chen Y]]
[[Category: Li, C L]]
[[Category: Duh Y]]
[[Category: Yuan, H S]]
[[Category: Hsiao Y-Y]]
[[Category: Dna processing]]
[[Category: Li C-L]]
[[Category: Dna repair]]
[[Category: Yuan HS]]
[[Category: Exonuclease]]
[[Category: Hydrolase-dna complex]]
[[Category: Tim barrel]]

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