5k2c: Difference between revisions
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==1.9 angstrom A2a adenosine receptor structure with sulfur SAD phasing and phase extension using XFEL data== | ==1.9 angstrom A2a adenosine receptor structure with sulfur SAD phasing and phase extension using XFEL data== | ||
<StructureSection load='5k2c' size='340' side='right' caption='[[5k2c]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5k2c' size='340' side='right'caption='[[5k2c]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5k2c]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K2C OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5k2c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K2C FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k2c OCA], [https://pdbe.org/5k2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k2c RCSB], [https://www.ebi.ac.uk/pdbsum/5k2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k2c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5k2c" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5k2c" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Aquila | [[Category: Escherichia coli]] | ||
[[Category: Barty | [[Category: Homo sapiens]] | ||
[[Category: Batyuk | [[Category: Large Structures]] | ||
[[Category: Boutet | [[Category: Aquila A]] | ||
[[Category: Cherezov | [[Category: Barty A]] | ||
[[Category: Fromme | [[Category: Batyuk A]] | ||
[[Category: Boutet S]] | |||
[[Category: Galli | [[Category: Cherezov V]] | ||
[[Category: Gati | [[Category: Fromme P]] | ||
[[Category: Han | [[Category: Galli L]] | ||
[[Category: Hunter | [[Category: Gati C]] | ||
[[Category: Ishchenko | [[Category: Han GW]] | ||
[[Category: James | [[Category: Hunter MS]] | ||
[[Category: Katritch | [[Category: Ishchenko A]] | ||
[[Category: Lee | [[Category: James D]] | ||
[[Category: Li | [[Category: Katritch V]] | ||
[[Category: Liang | [[Category: Lee M-Y]] | ||
[[Category: Liu | [[Category: Li C]] | ||
[[Category: Liu | [[Category: Liang M]] | ||
[[Category: Nelson | [[Category: Liu W]] | ||
[[Category: Popov | [[Category: Liu Z-J]] | ||
[[Category: Pu | [[Category: Nelson G]] | ||
[[Category: Spence | [[Category: Popov P]] | ||
[[Category: Stauch | [[Category: Pu M]] | ||
[[Category: Stevens | [[Category: Spence JCH]] | ||
[[Category: Weierstall | [[Category: Stauch B]] | ||
[[Category: White | [[Category: Stevens RC]] | ||
[[Category: Zhao | [[Category: Weierstall U]] | ||
[[Category: White TA]] | |||
[[Category: Zhao Y]] | |||