8prk: Difference between revisions

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OCA

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 ==THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS==
-<StructureSection load='8prk' size='340' side='right' caption='[[8prk]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
+<StructureSection load='8prk' size='340' side='right'caption='[[8prk]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[8prk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PRK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=8PRK FirstGlance]. <br>
+<table><tr><td colspan='2'>[[8prk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PRK FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8prk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8prk OCA], [https://pdbe.org/8prk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8prk RCSB], [https://www.ebi.ac.uk/pdbsum/8prk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8prk ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=8prk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8prk OCA], [http://pdbe.org/8prk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=8prk RCSB], [http://www.ebi.ac.uk/pdbsum/8prk PDBsum]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/IPYR_YEAST IPYR_YEAST]
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pr/8prk_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pr/8prk_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 29: / Line 31: @@
 ==See Also==
-*[[Inorganic pyrophosphatase|Inorganic pyrophosphatase]]
+*[[Inorganic pyrophosphatase 3D structures|Inorganic pyrophosphatase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Atcc 18824]]
+[[Category: Large Structures]]
-[[Category: Inorganic diphosphatase]]
+[[Category: Saccharomyces cerevisiae]]
-[[Category: Cooperman, B S]]
+[[Category: Cooperman BS]]
-[[Category: Goldman, A]]
+[[Category: Goldman A]]
-[[Category: Heikinheimo, P]]
+[[Category: Heikinheimo P]]
-[[Category: Hyytia, T]]
+[[Category: Hyytia T]]
-[[Category: Kajander, T]]
+[[Category: Kajander T]]
-[[Category: Kapyla, J]]
+[[Category: Kapyla J]]
-[[Category: Lahti, R]]
+[[Category: Lahti R]]
-[[Category: Torkkel, T]]
+[[Category: Torkkel T]]
-[[Category: Tuominen, V]]
+[[Category: Tuominen V]]
-[[Category: 2-metal ion mechanism]]
-[[Category: Enzyme mechanism]]
-[[Category: Hydrolase]]
-[[Category: Iorganic pyrophosphatase]]
-[[Category: Mutant structure]]