4rob: Difference between revisions

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-'''Unreleased structure'''
-The entry 4rob is ON HOLD  until Paper Publication
+==2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae==
+<StructureSection load='4rob' size='340' side='right'caption='[[4rob]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4rob]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ROB FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rob OCA], [https://pdbe.org/4rob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rob RCSB], [https://www.ebi.ac.uk/pdbsum/4rob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rob ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SP2_ANOGA SP2_ANOGA] Serine protease inhibitor that functions in the melanization-mediated immune response (PubMed:16113656, PubMed:20953892, PubMed:33520733, PubMed:33045027, PubMed:21465556, PubMed:25525260). By preventing the activation of phenoloxidases through the inhibiting of serine proteases CLIPB9 and CLIPB10, negatively regulates melanization in the hemolymph (PubMed:16113656, PubMed:20953892, PubMed:33520733, PubMed:33045027, PubMed:21465556, PubMed:25525260). By preventing melanization, has a detrimental role during P.berghei parasite mediated-infection and invasion of the mosquito midgut (PubMed:16113656).<ref>PMID:16113656</ref> <ref>PMID:20953892</ref> <ref>PMID:21465556</ref> <ref>PMID:25525260</ref> <ref>PMID:33045027</ref> <ref>PMID:33520733</ref>
-Authors: Lovell, S., Battaile, K.P., Zhang, X., Meekins, D.A., An, C., Michel, K.
+==See Also==
+*[[Serpin 3D structures|Serpin 3D structures]]
-Description: 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Anopheles gambiae]]
+[[Category: Large Structures]]
+[[Category: An C]]
+[[Category: Battaile KP]]
+[[Category: Lovell S]]
+[[Category: Meekins DA]]
+[[Category: Michel K]]
+[[Category: Zhang X]]