4qn2: Difference between revisions

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==2.6 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) in complex with NAD+ and BME-free Cys289==
==2.6 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) in complex with NAD+ and BME-free Cys289==
<StructureSection load='4qn2' size='340' side='right' caption='[[4qn2]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='4qn2' size='340' side='right'caption='[[4qn2]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qn2]] is a 8 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ni4 4ni4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QN2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QN2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qn2]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ni4 4ni4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QN2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mpb|4mpb]], [[4mpy|4mpy]], [[4nea|4nea]], [[4q92|4q92]], [[4nu9|4nu9]], [[4qje|4qje]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Betaine-aldehyde_dehydrogenase Betaine-aldehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.8 1.2.1.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qn2 OCA], [https://pdbe.org/4qn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qn2 RCSB], [https://www.ebi.ac.uk/pdbsum/4qn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qn2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qn2 OCA], [http://pdbe.org/4qn2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qn2 RCSB], [http://www.ebi.ac.uk/pdbsum/4qn2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qn2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0H2X0S3_STAAC A0A0H2X0S3_STAAC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]]
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Betaine-aldehyde dehydrogenase]]
[[Category: Large Structures]]
[[Category: Anderson, W F]]
[[Category: Staphylococcus aureus subsp. aureus COL]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Chen, C]]
[[Category: Chen C]]
[[Category: Halavaty, A S]]
[[Category: Halavaty AS]]
[[Category: Joo, J C]]
[[Category: Joo JC]]
[[Category: Minasov, G]]
[[Category: Minasov G]]
[[Category: Yakunin, A F]]
[[Category: Yakunin AF]]
[[Category: Betb]]
[[Category: Csgid]]
[[Category: Nad]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Oxidoreductase]]
[[Category: Rossmann fold]]

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