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==Phospho-glucan bound structure of starch phosphatase Starch EXcess4 reveals the mechanism for C6-specificty==
==Phospho-glucan bound structure of starch phosphatase Starch EXcess4 reveals the mechanism for C6-specificty==
<StructureSection load='4pyh' size='340' side='right' caption='[[4pyh]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4pyh' size='340' side='right'caption='[[4pyh]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pyh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PYH FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pyh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PYH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nme|3nme]], [[4kyq|4kyq]], [[4kyr|4kyr]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PRD_900035:alpha-maltohexaose'>PRD_900035</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DSP4, PTPKIS1, SEX4, At3g52180, F4F15.290 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pyh OCA], [https://pdbe.org/4pyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pyh RCSB], [https://www.ebi.ac.uk/pdbsum/4pyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pyh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pyh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pyh RCSB], [http://www.ebi.ac.uk/pdbsum/4pyh PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DSP4_ARATH DSP4_ARATH]] Starch granule-associated phosphoglucan phosphatase involved in the control of starch accumulation. Acts as major regulator of the initial steps of starch degradation at the granule surface. Functions during the day by dephosphorylating the night-accumulated phospho-oligosaccharides. Can release phosphate from both the C6 and the C3 positions.<ref>PMID:16513634</ref> <ref>PMID:16623901</ref> <ref>PMID:16772378</ref> <ref>PMID:19754155</ref> <ref>PMID:19141707</ref> <ref>PMID:20018599</ref> <ref>PMID:22100529</ref> <ref>PMID:22321580</ref> <ref>PMID:20679247</ref>
[https://www.uniprot.org/uniprot/DSP4_ARATH DSP4_ARATH] Starch granule-associated phosphoglucan phosphatase involved in the control of starch accumulation. Acts as major regulator of the initial steps of starch degradation at the granule surface. Functions during the day by dephosphorylating the night-accumulated phospho-oligosaccharides. Can release phosphate from both the C6 and the C3 positions.<ref>PMID:16513634</ref> <ref>PMID:16623901</ref> <ref>PMID:16772378</ref> <ref>PMID:19754155</ref> <ref>PMID:19141707</ref> <ref>PMID:20018599</ref> <ref>PMID:22100529</ref> <ref>PMID:22321580</ref> <ref>PMID:20679247</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4pyh" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Kooi, C W.Vander]]
[[Category: Large Structures]]
[[Category: Meekins, D A]]
[[Category: Meekins DA]]
[[Category: Carbohydrate binding]]
[[Category: Vander Kooi CW]]
[[Category: Chloroplast]]
[[Category: Dual-specificity phosphatase]]
[[Category: Hydrolase]]
[[Category: Starch phosphatase]]

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