4px2: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4px2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PX2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4px2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PX2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2WY:N-[(R)-1-BENZOFURAN-2-YL(PHENYL)METHYL]-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE-7-SULFONAMIDE'>2WY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2WY:N-[(R)-1-BENZOFURAN-2-YL(PHENYL)METHYL]-3,4-DIHYDRO-2H-1,5-BENZODIOXEPINE-7-SULFONAMIDE'>2WY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4px2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4px2 OCA], [https://pdbe.org/4px2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4px2 RCSB], [https://www.ebi.ac.uk/pdbsum/4px2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4px2 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4px2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4px2 OCA], [https://pdbe.org/4px2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4px2 RCSB], [https://www.ebi.ac.uk/pdbsum/4px2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4px2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Latest revision as of 20:24, 20 September 2023
Human GKRP bound to AMG2882 and Sorbitol-6-PhosphateHuman GKRP bound to AMG2882 and Sorbitol-6-Phosphate
Structural highlights
FunctionGCKR_HUMAN Inhibits glucokinase by forming an inactive complex with this enzyme. See Also |
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